[PDF.58jv] Genetic Modulators of Pulmonary Function in Cystic Fibrosis & Genetic Susceptibility Factors of Emphysema

Genetic Modulators of Pulmonary Function in Cystic Fibrosis & Genetic Susceptibility Factors of Emphysema

[PDF.ti46] Genetic Modulators of Pulmonary Function in Cystic Fibrosis & Genetic Susceptibility Factors of Emphysema

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 | #14474169 in Books |  2005-11-30 | Original language:English |  9.45 x.39 x6.30l, | File type: PDF | 172 pages

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This is a Ph.D. thesis. CF is one of the most common lethal autosomal recessive affecting the Caucasian population with an incidence of about 1 in 2500 births. Clinical manifestations are attributed to mutations in the CFTR gene, which encodes an epithelial chloride channel.

Specific mutations can influence the severity and progression of CF disease, but wide variations within genetically homogenous subgroups illustrate that other determinants of the clinical stat...

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